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Effect of THRIVE on safe apnea time in patients undergoing acute aortic dissection type A

Effect of THRIVE on safe apnea time in patients undergoing acute aortic dissection type A: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070464
Enrollment
Unknown
Registered
2023-04-12
Start date
2023-04-30
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Aortic Dissection Type A (ATAAD)

Interventions

THRIVE group:Transnasal Humidified Rapid Insufflation Ventilatory Exchange (THRIVE)
Facemask group:Facemask

Sponsors

Nanjing First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients undergoing emergency type A aortic dissection; 2. Aged >18 years; 3. In line with ethics, patients volunteered to be tested and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Awake intubation or delayed sequential intubation; 2. Patients with difficulty in endotracheal intubation (such as Mahali grade ? or above, restricted mouth opening, nachymental distance 40]; 3. Uncorrectable shock or cardiac arrest before surgery; 4. Inability to place a nasal oxygen tube due to suspected or confirmed skull base fracture or severe facial trauma; 5. Allergic to propofol, egg, soy or egg white; 6. Pregnant patients; 7. The researcher thinks it is not suitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
Safe apnoea time;

Secondary

MeasureTime frame
Intubation attempts;Adverse events during induction;Periintubation minimum oxygen saturation (SpO2);General information and airway assessment;Use of drugs;Time to regain baseline SpO2;Cormack-Lehane grade;Haemoglobin concentration;PaCO2;pH;PaO2;

Countries

China

Contacts

Public ContactShi Hongwei

Nanjing First Hospital

mdshw@163.com+86 13952095550

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026