atrial fibrillation
Conditions
Interventions
left atrial substrate modification first group:left atrial substrate modification first
pulmonary vein isolation first group:pulmonary vein isolation first
Sponsors
The Third People's Hospital of Chengdu
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 80 years; 2. Persistent atrial fibrillation: continuous attack >7 days, unable to spontaneously cardioversion or cardioversion under intervention measures (drug cardioversion or electric cardioversion); 3. Patients who are willing to accept this study program in our center; 4. Those who signed the informed consent for this study.
Exclusion criteria
Exclusion criteria: 1. History of left atrial catheter ablation; 2. Atrial fibrillation caused by reversible pathologic factors such as hyperthyroidism, drug or alcohol poisoning; 3. The patient had left atrial thrombosis or other absolute contraindications for catheter ablation; 4. Left ventricular insufficiency (LVEF=60mm; 6. Patients with severe liver diseases, renal insufficiency (eGFR<30mL/min), malignant tumors, autoimmune diseases, end-stage heart failure, and life expectancy within 1 year; 7. Patients who are participating in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether atrial fibrillation was terminated during the procedure;Whether atrial fibrillation recurred within 1 year after ablation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severe surgery-related complications (Pulmonary vein stenosis, cardiac tamponade, thromboembolism); | — |
Countries
China
Contacts
Public ContactLiu Hanxiong
The Third People's Hospital of Chengdu
Outcome results
None listed