brain injury
Conditions
Interventions
ICP group:N/A
non-ICP group:N/A
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult, no gender limit, aged >=18 years; 2. Acute brain injury due to hemorrhagic causes, including subarachnoid hemorrhage, cerebral hemorrhage, or craniocerebral trauma; 3. When admitted to ICU, Glasgow Coma Scale (GCS) score eye opening =1 point (stimulation did not open eyes), exercise score <=5 points (exercise without compliance), or neurological function deterioration within 48 hours after admission to ICU, GCS score eye opening =1 point (stimulation did not open eyes), exercise score <=5 points (exercise without compliance); 4. Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. The brain injury did not reach the corresponding severity degree and was not admitted to the intensive care unit; 2. Patients with craniocerebral injury caused by intracranial infection, cerebral ischemia, congenital malformations, autoimmune encephalitis, and craniocerebral tumors; 3. Complicated with systemic malignant tumor, acute stage or functional decompensation of major systemic and organ diseases; 4. Patients of childbearing age who do not use effective contraception and have no record of negative pregnancy tests; 5. Undergoing experimental drug or device testing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurological outcome 6 months after onset;Mortality 6 months after onset; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological outcome in ICU;Neurological outcome at discharge;Mortality in ICU;Mortality at discharge; | — |
Countries
China
Contacts
Public ContactGao Guoyi
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed