functional constipation
Conditions
Interventions
control group:Take maltodextrin
intervention group A:Take Qingchang capsule
intervention group B:Take aperient powder
Sponsors
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 45-65 years; 2. Meet the Rome IV diagnostic criteria for functional constipation (also known as habitual constipation), spontaneous defecation less than 3 times per week; 3. Voluntary and able to comply with test requirements, timely return visit and signed informed consent and confidentiality agreement.
Exclusion criteria
Exclusion criteria: 1. Those who cannot eat by mouth or take the test sample as prescribed; 2. Those who have unclear chief complaint or are too weak to conduct the experiment; 3. Patients with constipation symptoms caused by surgical operations within 30 days or with a history of colon/anal operations; 4. Recent defecation difficulties caused by organoplasmic diseases (colon cancer, severe enteritis, intestinal obstruction, inflammatory bowel disease, etc.); 5. Difficulty in defecation accompanied by pain; 6. Patients with acute gastrointestinal disease within 30 days; 7. Pregnant and menstruating patients; 8. Patients with serious systemic diseases such as cardiovascular, liver, kidney and hematopoietic system; 9. Those who are being treated for other concomitant diseases; 10. Recent use of medicinal foods that may affect constipation symptoms and/or intestinal flora composition, such as antibiotics, laxatives or diuretics, prebiotics, probiotics, etc.; 11. Other conditions for which participation in the trial is not considered appropriate by the doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| status of defecation;Bristol Stool Scale;quality of life;gut microbiota;body mass index;blood pressure;other anthropometric measurements;dietary intake; | — |
Countries
China
Contacts
Public ContactYing Chenjiang
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed