Knee osteoarthritis
Conditions
Interventions
Sponsors
The Third Affiliated Hospital of He'nan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1 Inclusion criteria for patients with knee osteoarthritis: (1) Meet the diagnostic criteria of KOA; (2) Aged 40-70 years; (3) Report knee pain for more than 3 months; (4) The pain score on the digital rating scale (NRS) was greater than 3 points; (5) Kellgren-Lawrence score: 2 or 3. 2. Inclusion criteria of healthy volunteers: (1) Aged 40-70 years; (2) No history of chronic pain.
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients with knee osteoarthritis: 1. Those who have received any other treatment within the last 1 month; 2. Pregnant or lactating patients; 3. Suffering from mental, neurological, infectious, gastrointestinal, cardiovascular, cerebrovascular, immunological, respiratory or renal diseases; 4. Have cancer, tuberculosis, rheumatism or rheumatoid arthritis, gout, joint trauma, or any other chronic pain symptoms, or have a history of brain trauma with loss of consciousness; 5. Patients with MRI contraindications such as atrexia phobia, cardiac pacemaker, defibrillator, heart stent and intrauterine device.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI neuroimaging indices;Numerical Rating Scale;Hamilton Depression Scale;Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pressure pain thresholds; | — |
Countries
China
Contacts
Public ContactXu Hui
The Third Affiliated Hospital of He'nan University of Chinese Medicine
Outcome results
None listed