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The analgesic effect of serratus anterior plane block after hepatectomy with right subcostal incision: a single center, randomized, double-blind controlled clinical trial

The analgesic effect of serratus anterior plane block after hepatectomy with right subcostal incision: a single center, randomized, double-blind controlled clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070437
Enrollment
Unknown
Registered
2023-04-12
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia

Interventions

SAPB+RSB group:ultrasound-guided serratus anterior plane block (10 ml of 1% ropivacaine and 10ml 1% lidocaine) and rectus sheath plane block (10 ml of 1 % ropivacaine and 10ml 1% lidocaine)
Control group:no nerve block was performed

Sponsors

The Third Affiliated Hospital of Naval Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 20-80 years, with ASA grade I-?, were selected for subcostal incision surgery due to hepatobiliary diseases. 2. Tumors 50% in patients with cirrhosis, but > 35% in patients without cirrhosis. 3. Child A or B.

Exclusion criteria

Exclusion criteria: 1. Patients with major organ insufficiency. 2. Patients with severe sinus delay or degree II type II block. 3. Patients with mental and psychological problems and language barriers. 4. Patients with chronic pain and long-term use of various painkillers. 5. History of abdominal surgery or trauma, abnormal liver tumor or bleeding history, emergency surgery, intraoperative blood transfusion, operation time >5 hours or operation time 26kg/m^2, currently taking birth control pills, pregnant. 7. Contraindications of peripheral nerve block, such as allergy to local anesthetics, local or systemic infection, and coagulation disease. 8. Incomplete intraoperative hemostasis requires gauze packing for hemostasis and postoperative surgical complications such as bleeding, biliary fistula or surgical intervention.

Design outcomes

Primary

MeasureTime frame
Sufentanil consumption 48 hours after surgery;

Secondary

MeasureTime frame
The first time of use PCA after surgery;Frequency and dose of remedial analgesia;Postoperative pain score;

Countries

China

Contacts

Public ContactChen Qianbo

The Third Affiliated Hospital of Naval Military Medical University

qianbo1984chen@163.com+86 13774288357

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026