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Effect of esketamine on postoperative patient-controlled analgesia in children with limb fracture

Effect of esketamine on postoperative patient-controlled analgesia in children with limb fracture

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070434
Enrollment
Unknown
Registered
2023-04-12
Start date
2023-04-11
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

children with limb fracture

Interventions

Esketamine combined with sufentanil group:Esketamine combined with sufentanil for patient-controlled intravenous analgesia pump
Sufentanil group:Sufentanil for patient-controlled intravenous analgesia pump

Sponsors

The First People's Hospital of Lianyungang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Aged 2-7 years; 2. New cases of traumatic fracture; 3. ASA grading ?-?; 4. Obtain the informed consent of the guardian of the child; 5. BMI 13-20 kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Severe congenital disease or congenital disease that researchers believe will affect the results of the experiment; 2. Patients with history of bronchial asthma; 3. Abnormal heart, lung, liver and kidney function; 4. Patients who are allergic to the drug ingredients in this study; 5. Patients with mental and cognitive disorders that researchers believe may have influenced the experimental results.

Design outcomes

Primary

MeasureTime frame
FLACC analgesia score at 48 hours after surgery;

Secondary

MeasureTime frame
Ramsay sedation score at 48 hours postoperatively;PCA sufentanil usage at 48 hours postoperatively;Number of effective PCA compressions at 48 hours postoperatively;Parental satisfaction with pain control;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactChen Ying

The First People's Hospital of Lianyungang

1450394282@qq.com+86 18961322003

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026