Indeterminate Biliary Strictures
Conditions
Interventions
dilation catheter-guided mini-forceps biopsy group:dilation catheter-guided mini-forceps biopsy
cholangioscopy-guided forceps biopsy group:cholangioscopy-guided forceps biopsy
Sponsors
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 88 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18-88 years; 2. Willing and able to comply with the study procedures and provide written informed consent to participate in the study; 3. Biliary obstructive symptoms,or indeterminate biliary stricture suspected to be intrinsic based on prior imaging; 4. With ERCP indications.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot tolerate endoscopic examination; 2. Patients with endoscopy or anesthesia contraindications; 3. Patients with coagulation dysfunction; 4. Abdominal pain due to functional gastrointestinal disease; 5. Enrolled in other clinical trials 3 months before onset; 6. Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of dilation catheter-guided mini-forceps biopsy or cholangioscopy-guided forceps biopsy findings;Sensibility;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time;Technical success rate;Obtain pathological tissue quality;Adverse event occurrence rate;Cost benefit ratio; | — |
Countries
China
Contacts
Public ContactLi Baiwen
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed