Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
Conditions
Interventions
Experimental group:Received auxiliary treatment with Hydrogen-Oxygen Generator with Nebulizer
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years, no gender limit; 2. Subjects with clinically confirmed AECOPD; 3. Use hydrogen and oxygen atomizer for auxiliary treatment; 4. Participate in the study voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects with known intolerance to inhalation therapy; 2. Subjects with mental illness or moderate or above disability; 3. Pregnant or lactating female subjects; 4. Subjects assessed by the researcher as unfit to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of device-related adverse events within 12 months of treatment;Change of BCSS score from baseline; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of acute exacerbations within 12 months of treatment;Time from baseline to the first acute exacerbation;Change of COPD Assessment Test (CAT) score from baseline;Changes in pulmonary function indicators (FVC, FEV1, FEV1/FVC, and PEF) from baseline;Change in 6 Minutes Walking Distance (6MWD) from baseline;Times and days of inpatient/outpatient treatment of AECOPD; | — |
Countries
China
Contacts
Public ContactZhong Nanshan, Zheng Zeguang
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed