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Effect of Berberine on Cognition and Metabolism of Schizophrenia

Effect of Berberine on Cognition and Metabolism of Schizophrenia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070415
Enrollment
Unknown
Registered
2023-04-11
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Control group:Placebo

Sponsors

Suzhou Guangji Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for ''schizophrenia'' in the World Health Organization Category Directory of Mental and Behavioural Disorders (ICD-11); 2. No gender limit, aged between 16 and 60 years; 3. The patient himself or his family members voluntarily participated in the study and signed the informed consent; 4. Primary school or above education level, able to understand the assessment methods, content and process in this study after explanation.

Exclusion criteria

Exclusion criteria: 1. Suffering from the following diseases: epilepsy and other neurological diseases, acute and chronic renal failure, severe diabetes, heart, liver, kidney, endocrine and metabolic system, blood system and other physical diseases or diseases that may interfere with the test evaluation; 2. Drug addicts and other psychoactive substances; 3. Color blind, color weak, non-right-handed.

Design outcomes

Primary

MeasureTime frame
Positive and Negative Symptom Scale (PANSS);Cambridge Neuropsychological Test Automatic Battery (CANTAB);Nicotinic acid skin test;

Secondary

MeasureTime frame
Fasting blood glucose, fasting insulin;Four items of blood lipid;Antioxidant factor index;Blood routine;Blood biochemistry;Immune factor index;

Countries

China

Contacts

Public ContactYang Yong

Suzhou Guangji Hospital

szgjyy@126.com+86 15306212978

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026