None listed
Conditions
Interventions
Control group:PCIA was used after surgery. The analgesic drug was formulated as hydromorphone 10mg+ Ondansetron 8mg+0.9% normal saline 100ml, background dose 2ml/h, single supplementary dose 2ml, lock
Lidocaine group 1:During anesthesia induction, lidocaine was injected 1mg/kg intravenously (slowly within 10 minutes), and then lidocaine was pumped 1.5mg/kg/h until the patient left the room. The pos
Lidocaine group 2:During anesthesia induction, lidocaine was injected 1mg/kg intravenously (slowly within 10 minutes), and then lidocaine was pumped 1.5mg/kg/h until the patient left the room. The pos
Sponsors
Tai 'an Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. American Society of Anesthesiologists (ASA) Grade 1-2; 3. Sign informed consent to accept postoperative controlled intravenous analgesia (PCIA).
Exclusion criteria
Exclusion criteria: 1. Previous history of chest surgery; 2. Allergic to opioid analgesics; 3. Mental diseases; 4. Severe dysfunction of heart, lung, liver, kidney and other vital organs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting (PONV) within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative resting and motor pain scores;PONV severity;Recovery time of gastrointestinal function;Related indicators of inflammatory stress response;Immune related indicators;Postoperative skin itching, respiratory depression, and incidence of chronic pain; | — |
Countries
China
Contacts
Public ContactYang Zaiqi
Tai 'an Central Hospital
Outcome results
None listed