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Correlation between blood stasis syndrome score and coronary calcification score and SIRT1 level of peripheral blood mononuclear cells in patients with diabetic coronary calcification (DM-CAC)

Correlation between blood stasis syndrome score and coronary calcification score and SIRT1 level of peripheral blood mononuclear

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070385
Enrollment
Unknown
Registered
2023-04-11
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type2 diabetes mellitus coronary artery calcification

Interventions

DMCAC group:N/A
DM-nonCAC:N/A

Sponsors

Xiyuan Hospital of CACMS
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 74 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of type 2 diabetes; (2) the age is between 35 and 74 years old; (3) For those who underwent coronary CTA in recent one year, the image data are clear and complete for analysis; (4) Informed consent.

Exclusion criteria

Exclusion criteria: (1) According to the medical history, color Doppler ultrasound and CTA, there are other vascular calcifications except coronary artery; (2) Patients diagnosed with acute coronary syndrome in recent 3 months; (3) Patients with cardiac insufficiency, valvular heart disease and various types of cardiomyopathy; (4) Patients with kidney disease and diabetic nephropathy, including abnormal renal function, massive albuminuria, and diabetic nephropathy. Retinopathy with microalbuminuria; (5) Patients with acute and chronic infection, stroke, severe primary diseases of liver, lung, thyroid and blood system; (6) Patients with peripheral vascular diseases or thrombotic diseases in the past six months.

Design outcomes

Primary

MeasureTime frame
General Information;Comorbidities and treatment history;CACS;Blood stasis syndrome score;The level of SIRT1 of PBMC;

Countries

China

Contacts

Public Contactyue liu

Xiyuan Hospital of CACMS

liuyue@188.com+86 13700167815

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026