Osteoarthritis of knee
Conditions
Interventions
exercise group:exercise treatment
electroacupuncture group:electroacupuncture
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients will be eligible if they : (I) aged 45-75, any gender; (2) meet the American College of Rheumatology (ACR) diagnostic criteria of KOA; (3) have knee pain for more than 3 month; (4) have radiological examination within 6 months indicating II or III in Kellgren-Lawrence grade with medial more than lateral tibiofemoral osteoarthritis in at least one knee; (5) score 4 or greater in numerical rating scale (NRS) during flat walking for the past week; (6) are willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: Patients will be ineligible if meet the following points: (1) history of knee surgery for the evaluating knee or waiting for any surgery for either knee; (2) knee pain due to other diseases (eg meniscus tear, rheumatoid arthritis, joint cavity infection, malignancy, gout, lumbosacral diseases with symptom of lower extremity, etc.); (3) arthroscopy history within 1 year or intraarticular injection history within 6 months for the evaluating knee; (4) either knee received acupuncture/exercise therapy for the last 6 months; (5) severe acute or chronic organic or neuropsychiatric disorder; (6) disorders of coagulopathy (eg hemophilia); (7) pacemakers or epilepsy; (8) pregnancy preparation, pregnant or lactation period; (9) participated in other clinical studies within the past 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in numerical rating scale;Osteoarthritis Outcome Score (KOOS) Function in daily living (ADL); | — |
Secondary
| Measure | Time frame |
|---|---|
| patient's global assessment (PGA);Knee injury and Osteoarthritis Outcome Score (KOOS) Pain;KOOS knee-related Quality of Life (QOL);Credibility/Expectancy Questionnaire;30-second Chair Stand Test (30s-CST);40m (4x10m) Fast Paced Walk Test (40m FPWT);Daily Physical Activity level (DPA);Short Form 6 Dimensions (SF-6D);Five-level EuroQol five-dimensional questionaire (EQ-5D-5L);rescue medicine;adverse event; | — |
Countries
P.R.China
Contacts
Public ContactLin Jianhao;Liu Cunzhi
Peking University People's Hospital; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine
Outcome results
None listed