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Research on DNA Methylation Biomarkers in Epithelial Ovarian Cancer

Research on DNA Methylation Biomarkers in Epithelial Ovarian Cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070352
Enrollment
Unknown
Registered
2023-04-10
Start date
2022-10-10
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Cancer

Interventions

Index test:methylation targeted sequencing, CpG probes

Sponsors

Beijing Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with epithelial ovarian cancer 1. Female aged 18-80; 2. The initial histopathological diagnosis was primary epithelial ovarian malignant tumor; Patients with benign ovarian tumors 1. Female aged 18-80; 2. Primary epithelial ovarian benign tumor was diagnosed by histopathology; Collection of normal control samples 1. Female aged 18-80; 2. Patients with ovariectomized due to uterine prolapse, endometrial polyps or hysteromyoma and other non ovarian related benign diseases.

Exclusion criteria

Exclusion criteria: 1. Patients with other malignant tumors; 2. Pregnant women, patients within 6 weeks after delivery and lactation; 3. The clinical histopathological results cannot be obtained subsequently, follow-up cannot be conducted, or the research is terminated for any other reason; 4. Any other circumstances that are not suitable for this study.

Design outcomes

Primary

MeasureTime frame
Receiver Operator Characteristic Curve;

Secondary

MeasureTime frame
sensitivity;specificity;Concordance correlation coefficent;Missed diagnosis rate;misdiagnosis rate;positive predictive value;Negative predictive value;

Countries

China

Contacts

Public ContactQian Hu

Beijing Hospital

flushaa@163.com+86 13701398423

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026