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Molecular mechanism of EGFR regulation of neutrophil activation and degranulation in sepsis

Molecular mechanism of EGFR regulation of neutrophil activation and degranulation in sepsis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070350
Enrollment
Unknown
Registered
2023-04-10
Start date
2022-06-19
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients or their family members gave informed consent to the study and signed informed consent 2. healthy subjects in physical examination center and hospitalized patients with sepsis 3. Male and female, above 18 years old 4. Patients without other serious systemic diseases

Exclusion criteria

Exclusion criteria: 1. Accompanied by serious diseases of heart, liver, kidney and hematopoietic system 2. Patients with malignant tumor 3. Patients with central nervous system and psychological disorders before surgery

Design outcomes

Primary

MeasureTime frame
Expression of EGFR on neutrophils;

Countries

China

Contacts

Public ContactJing Tang

Affiliated Hospital of Guangdong Medical University

tanglitangjing@126.com+86 13189091282

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026