Parkinson's disease
Conditions
Interventions
Experimental group :Measuring range of eye motion
Experimental group :Levodopa challenge test
Health control :Measuring range of eye motion
Sponsors
First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with Parkinson 's disease meet 2015-MDS Parkinson 's diagnostic criteria. 2. H / Y rating of 1-4. 3. Less than 10 years of onset with no significant neck stiffness. 4. MMSE score greater than or equal to 24 points, visual and auditory normal, can cooperate to complete the test. 5. No basic ophthalmic diseases, such as eye infection, refractive error, glaucoma, cataract and other diseases.
Exclusion criteria
Exclusion criteria: 1. Cerebral hemorrhage, cerebral infarction, poisoning, trauma can lead to clear cause of Parkinson ' s disease. 2. Patients with eye infection, glaucoma, cataract, previous trauma or skin defect. 3. Patients with atypical parkinsonism, such as progressive supranuclear palsy, multiple system atrophy, corticobasal degeneration, vascular parkinsonism, dementia with Lewy bodies, etc. 4. Patients with intracranial hypertension, epilepsy, pregnant women, elderly and infirm individuals who cannot cooperate to complete the experimental operation 5. Others who could not cooperate with the experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| upwards distance;downwards distance;leftwards distance;rightwards distance;Movement disorder society-unified-parkinson disease rating scale; | — |
Countries
China
Contacts
Public ContactXianwen Chen
the First Affiliated Hospital of Anhui Medical University
Outcome results
None listed