Gastrointestinal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with malignant tumor confirmed by histology or cytology; 2. Peripheral neuropathy of grade 2 or above (NCI-CTCAE 4.0 grading standard) occurred after chemotherapy with mFOLFOX6 regimen; 3. Age >= 18 years old; 4. The expected survival time is more than 6 months; 5. Informed consent and voluntary participation in this study.
Exclusion criteria
Exclusion criteria: 1. Furuncle, obvious damage and unknown lump can be seen on the skin of scraping site; 2. People with bleeding tendency, contact dermatitis, and highly allergic skin; 3. Peripheral neuropathy caused by alcoholism and diabetes, as well as neurological symptoms caused by original cervical spondylosis, nervous system disease and brain metastasis; 4. Those with severe heart, brain, lung, liver, kidney and other primary diseases and systemic edema; 5. Severe bone metastasis (mainly refers to spine, scapula, rib, ilium, etc.); 6. Those who are participating in other relevant clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity Scale, FACT/GOG-Ntx; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numeric Rating Scale, NRS;Edmonton Symptom Assessment Scale, ESAS; | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Chinese Medicine