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Effect of Guasha therapy on oxaliplatin-induced peripheral neuropathy

Effect of Guasha therapy based on the theory of Si Jing Pai Du on oxaliplatin-induced peripheral neuropathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070295
Enrollment
Unknown
Registered
2023-04-07
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal cancer

Interventions

Experimental group:Guasha therapy, once a week for 4 weeks
control group:health education

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with malignant tumor confirmed by histology or cytology; 2. Peripheral neuropathy of grade 2 or above (NCI-CTCAE 4.0 grading standard) occurred after chemotherapy with mFOLFOX6 regimen; 3. Age >= 18 years old; 4. The expected survival time is more than 6 months; 5. Informed consent and voluntary participation in this study.

Exclusion criteria

Exclusion criteria: 1. Furuncle, obvious damage and unknown lump can be seen on the skin of scraping site; 2. People with bleeding tendency, contact dermatitis, and highly allergic skin; 3. Peripheral neuropathy caused by alcoholism and diabetes, as well as neurological symptoms caused by original cervical spondylosis, nervous system disease and brain metastasis; 4. Those with severe heart, brain, lung, liver, kidney and other primary diseases and systemic edema; 5. Severe bone metastasis (mainly refers to spine, scapula, rib, ilium, etc.); 6. Those who are participating in other relevant clinical trials.

Design outcomes

Primary

MeasureTime frame
Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity Scale, FACT/GOG-Ntx;

Secondary

MeasureTime frame
Numeric Rating Scale, NRS;Edmonton Symptom Assessment Scale, ESAS;

Countries

China

Contacts

Public ContactZhang Fuli

Guangdong Provincial Hospital of Chinese Medicine

zhangfuli1987@163.com+86 138 2440 1834

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026