Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnostic criteria for osteoarthritis of the knee; 2. 40-70 years of age; 3. Reported knee pain for more than 3 months; 4. Pain score of > 3 on the numeric rating scale (NRS); 5. Kellgren-Lawrence score: 2 or 3.
Exclusion criteria
Exclusion criteria: 1. Knee pain caused by other diseases; 2. Intra-articular injections within the past 6 months; 3. A history of knee surgery; 4. Have a severe acute or chronic organic disease or psychiatric illness; 5. Have a bleeding disorder; 6. Have contraindications to MRI, such as phobias, pacemakers, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI neuroimaging indices;Numerical rating scale;Hamilton Depression Scale;Western Ontario and McMaster Universities Osteoarthritis Index;Safety indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pressure pain thresholds; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Henan University of Chinese Medicine