obstetrics Disease
Conditions
Interventions
0.6mg/kg group:Remazolam concentration 0.6 mg/kg
0.1mg/kg group:remazolam concentration 0.1mg/kg
0.2mg/kg group:remazolam concentration 0.2mg/kg
0.4mg/kg group:remazolam concentration 0.4mg/kg
Sponsors
Obstetrics & Gynaecology Hospital, Fudan University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Adult female patients, aged from 20 to 40 years old, ASA I grade, BMI 19~24 kg/m2, elective surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with possible difficult airway: modified Mallampati score III grade or IV grade; 2. Anesthetic allergy or contraindication; 3. Patients who took benzodiazepine or opioid or intermittent benzodiazepine every day in the past 3 months or had a history of severe alcohol or drug abuse; 4. Patients with other systemic diseases; 5. Patients with communication difficulties.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation score, MOAA/S;Visual laryngoscope examination respiratory tract rating; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalogram index, BIS;Blood pressure, HBP;Heart rate, HR;Oxygen saturation, SpO2; | — |
Countries
China
Contacts
Public ContactYang Chen
Obstetrics & Gynaecology Hospital, Fudan University
Outcome results
None listed