Diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years; 2. Patients with type 2 diabetes and normoglycemia who need to undergo (have undergone) liver surgery; 3. Diabetes diagnosis criteria according to the American Diabetes Association (ADA) in 2011 or the World Health Organization (WHO) in 1999.
Exclusion criteria
Exclusion criteria: 1. Those with severe acute or chronic complications of diabetes; 2. Those with a history of pancreatitis; 3. Persons with severe systemic disease or organ failure; 4. Those receiving long-term systemic corticosteroid therapy, immunosuppressive or cytotoxic therapy; 5. Female patients with potential pregnancy or pregnant women; 6. Subjects with poor compliance or inability to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hepatic LCMR1 mRNA expression;Hepatic LCMR1 protein expression;Whole blood glucose hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral blood LCMR1 mRNA expression;Peripheral blood LCMR1 protein expression;Fasting blood glucose;Fasting serum insulin;Fasting serum C-peptide; | — |
Countries
China
Contacts
Chinese PLA General Hospital