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Correlation between type 2 diabetes mellitus and LCMR1 expression in liver and blood

Correlation between type 2 diabetes mellitus and LCMR1 expression in liver and blood

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070276
Enrollment
Unknown
Registered
2023-04-07
Start date
2023-04-07
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus

Interventions

Type 2 diabetes patients group:N/A
Healthy control group:N/A

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. Patients with type 2 diabetes and normoglycemia who need to undergo (have undergone) liver surgery; 3. Diabetes diagnosis criteria according to the American Diabetes Association (ADA) in 2011 or the World Health Organization (WHO) in 1999.

Exclusion criteria

Exclusion criteria: 1. Those with severe acute or chronic complications of diabetes; 2. Those with a history of pancreatitis; 3. Persons with severe systemic disease or organ failure; 4. Those receiving long-term systemic corticosteroid therapy, immunosuppressive or cytotoxic therapy; 5. Female patients with potential pregnancy or pregnant women; 6. Subjects with poor compliance or inability to cooperate.

Design outcomes

Primary

MeasureTime frame
Hepatic LCMR1 mRNA expression;Hepatic LCMR1 protein expression;Whole blood glucose hemoglobin;

Secondary

MeasureTime frame
Peripheral blood LCMR1 mRNA expression;Peripheral blood LCMR1 protein expression;Fasting blood glucose;Fasting serum insulin;Fasting serum C-peptide;

Countries

China

Contacts

Public ContactLiang'an Chen

Chinese PLA General Hospital

Chenla301@263.net+86 10 5549 9227

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026