Obese
Conditions
Interventions
Group LBW:lean body weight will be used as the dosing scalar of rocuronium and sugammadex
Group IBW:Ideal body weight will be used as the dosing scalar of rocuronium and sugammadex
Group TBW:Total body weight will be used as the dosing scalar of rocuronium and sugammadex
Sponsors
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18-65 years old, BMI = 30, ASA II-III, Gynecological laparoscopic surgery under general anesthesia, the duration from rocuronium induction to the end of surgery >= 1 hour.
Exclusion criteria
Exclusion criteria: Neuromuscular diseases; Received any medications which will interfere with the signal transmission of neuromuscular junction; Damage liver and kidney function; Allergy to research drugs; Predictable difficult airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average hourly rocuronium consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| the proportion of patients reached TOF=0 at 60s after the induction dose of rocuronium;Time to reappearance of TOFR >= 90% after sugammadex intervention;Surgeon's satisfaction rating of surgical vision;Time to the first supplementary rocuronium dose after intubation dose of rocuronium;The average dose of sugammadex sodium;the proportion of patients reached deep NMB when incision; | — |
Countries
China
Contacts
Public ContactZhao Na
Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Outcome results
None listed