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Analysis of the occurrence and treatment of enamel demineralization and gingivitis in adolescent orthodontic patients based on oral microecology

Analysis of the occurrence and treatment of enamel demineralization and gingivitis in adolescent orthodontic patients based on oral microecology

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070243
Enrollment
Unknown
Registered
2023-04-06
Start date
2023-05-20
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enamel demineration and gingivitis

Interventions

Placebo group:Placebo
Non-orthodontic group with uneven teeth:not
Tooth alignment group:not
Invisible appliance group:not
Self-locking bracket group:not
Metal bracket group:not
Fluoride intervention group:Fluorine varnish

Sponsors

Wuxi Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. The experimental process can abide by the relevant rules, aged 10-18 years old; 2. Good health, no history of serious chronic diseases or allergies; 3. No systemic diseases, not in pregnancy; 4. The DMFT of healthy caries-free children is 0, and the DMFT of children with caries is >= 6; 5. The deciduous teeth have all erupted and can cooperate with the examination; 6. The lifestyle during the study period remained unchanged.

Exclusion criteria

Exclusion criteria: 1. Have a systemic disease (such as diabetic nephropathy, autoimmune disease); 2. Systemic antibiotic therapy within 2 months or antibiotics taken within 1 month; 3. Received hormone and immunosuppressant therapy within 36 months; 4. Oral diseases such as acute pharyngitis acute tonsillitis appear in the mouth such as infected foci of gingivitis acute pharyngitis acute tonsillitis; 5. Currently have a smoking habit.

Design outcomes

Primary

MeasureTime frame
Enamel demineralization index;saliva IgA;Plaque flora;

Secondary

MeasureTime frame
saliva pH;plaque index;periodontal disease index;calculus index;Salivary flow;Bleeding index;

Countries

China

Contacts

Public ContactYanxiao Zhang

Wuxi Stomatological Hospital

1964993439@qq.com+86 18762636587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026