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Retrospective clinical study of COX-2 inhibitor in the treatment of COVID-19 pneumonia

Retrospective clinical study of COX-2 inhibitor in the treatment of COVID-19 pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070238
Enrollment
Unknown
Registered
2023-04-06
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Experimental group (specific COX-2 inhibitor Celecoxib):N/A
Control group (non-specific cyclooxygenase inhibitors):N/A

Sponsors

Chongqing University Three Gorges Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. COVID-19 nucleic acid test positive cases, and meet the diagnostic criteria of the Diagnosis and Treatment Plan for novel coronavirus Pneumonia (Tenth Edition for Trial Implementation); 2. Age is more than 14 years old; 3. The COX-2 inhibitor celecoxib, or highly selective non steroidal drugs such as ibuprofen, or non steroidal drugs not used at home, in the outpatient department or after admission, were taken for more than 1 day.

Exclusion criteria

Exclusion criteria: 1. Non COVID-19 pneumonia confirmed cases; 2. COVID-19 patients who did not use non steroidal drugs for less than 1 day; 3. Patients younger than 14 years old; 4. Missing clinical data.

Design outcomes

Primary

MeasureTime frame
IL-6;Symptom relief situation;

Secondary

MeasureTime frame
Nucleic acid conversion time;Adverse event occurrence rate;All-cause mortality rate;

Countries

China

Contacts

Public ContactWang Hailong

Chongqing University Three Gorges Hospital

wangjinlong2007666@163.com+86 159 2385 9880

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026