Influence of long-acting local anesthetic infiltration analgesia on surgical wound healing

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300070216

Enrollment

Unknown

Registered

2023-04-05

Start date

2023-04-01

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain

Interventions

bupivacaine liposome:bupivacaine liposome local infiltration

ropivacaine:ropivacaine subcutaneous analgesia

bupivacaine liposome :bupivacaine liposome local infiltration

control:no intervention

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65; 2. The ASA grade is I-III; 3. Thoracic and abdominal surgery patients (Class II clean wounds, such as liver surgery; III infected wounds, such as debridement and suture in plastic department +VSD surgery); 4. The patients were informed about the study and voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients allergic to local anesthetics; 2. Long-term use of psychotropic drugs, analgesics, and alcohol addiction; 3. Patients with abnormal liver and kidney function; 4. Suffering from immune-related diseases; 5. Patients with severe anemia or severe cachexia; 6. Diabetic patients with poor blood sugar control; 7. Patients with chronic pain; 8. Voluntary withdrawal of patients.

Design outcomes

Primary

Measure	Time frame
Total Sufentanil Dosage 48 hours after surgery;	—

Secondary

Measure	Time frame
wound healing;infection;visual analogue scale score;	—

Countries

China

Contacts

Public ContactTan Gang

Peking Union Medical College Hospital

tangang@pumch.cn+86 134 6670 5965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026