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The Effect of early intravenous amino acid supplementation in critically IlI patients with normaL kidney function on muscle metabolism

The Effect of early intravenous amino acid supplementation in critically IlI patients with normaL kidney function on muscle metabolism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070214
Enrollment
Unknown
Registered
2023-04-05
Start date
2023-04-05
Completion date
Unknown
Last updated
2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical illness

Interventions

All:None

Sponsors

Jinling Hospital affiliated to Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients recruited in the ESSENTIAL trial (ChiCTR2100053359) within 6 hours; 2. Informed consent form obtained from the patient or next of kin.

Exclusion criteria

Exclusion criteria: 1. There are contraindications for muscle biopsy (severe coagulation disorders, local infections, irritability, inability to cooperate, etc.); 2. Patients expected to be discharged (dead/transferred) within 7 days of enrollment.

Design outcomes

Primary

MeasureTime frame
28d ICU-freedays;—

Secondary

MeasureTime frame
Energy delivery;Protein delivery;New onset organ failure;New receipt of organ support therapy;Mortality;muscle biopsy indicators;—

Countries

China

Contacts

Public ContactWeiqin Li

Jinling Hospital affiliated to Nanjing University

ctgchina@medbit.cn+86 2580860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026