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The efficacy and mechanism of transauricular vagus nerve stimulation in the treatment of mild to moderate ulcerative colitis

The efficacy and mechanism of transauricular vagus nerve stimulation in the treatment of mild to moderate ulcerative colitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070196
Enrollment
Unknown
Registered
2023-04-04
Start date
2023-05-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ulcerative colitis

Interventions

experimental group :transauricular vagus nerve stimulation
control group :sham stimulation

Sponsors

Department of Gastroenterology, The First Affiliated Hospital of USTC Anhui Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who meet the diagnostic criteria for moderate and severe ulcerative colitis, with the symptom severity score of 6 to 12 points

Exclusion criteria

Exclusion criteria: Have a history of abdominal surgery; Organic diseases of digestive system (including polyps, inflammatory bowel diseases, tumors, celiac disease, lactose intolerance, etc.); B ultrasonic examination of patients with hepatobiliary and pancreatic diseases; People with hypertension and unstable blood pressure control; Have a history of diabetes, thyroid disease, systemic sclerosis, systemic lupus erythematosus, etc; Pregnant, lactating or planned pregnancy

Design outcomes

Primary

MeasureTime frame
Mayo score;

Secondary

MeasureTime frame
IBD quality of life score;Serum neurotransmitter TNF, IL-10;Blood biochemical indicators;

Countries

China

Contacts

Public ContactYue Yu

Anhui Provincial Hospital

yuyuedoctor@163.com13856238991

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026