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Exploring cerebral blood oxygen changes and central mechanisms in mild cognitive impairment (MCI) treated with acupuncture based on functional near infrared imaging (fNIRS)

Exploring cerebral blood oxygen changes and central mechanisms in mild cognitive impairment (MCI) treated with acupuncture based on functional near infrared imaging (fNIRS)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300070175
Enrollment
Unknown
Registered
2023-04-04
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Sponsors

Sichuan China 81 Rehabilitation Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meeting the diagnostic criteria for MCI. (2) Age 50 to 80 years, right-handed, male or female, with a disease duration of more than 3 months. (3) Clinical Dementia Rating Scale (CDR) score of less than 2 (4) Education level elementary school and above, able to understand and complete the scale correctly. (5) Have not received any acupuncture treatment within 6 months (6) Voluntary cooperation and signed informed consent form. Note: Patients who met both of these criteria were included in this study.

Exclusion criteria

Exclusion criteria: (1) Are receiving other treatments that may interfere with cognitive function, such as taking medications that affect cognition (donepezil, memantine, rivastigmine, etc.) (2) Have a history of neurological disorders (except for patients with early suspected Alzheimer's disease) confirmed by examination to affect cognitive function, including encephalitis, epilepsy, Parkinson's disease, vascular dementia, brain tumors, or traumatic brain injury that result in neurological damage and other structural brain abnormalities. (3) Those with a history of tumor, psychiatric disorders (e.g., bipolar disorder, schizophrenia), or severe anxiety (HAMA = 29) and depression (HAMD = 24). (4) The presence of prior alcohol, drug, or substance abuse that can impact on the evaluation of cognitive function (5) Those with bleeding disorders, bleeding tendencies, or severe skin infections (6) Those who have received any acupuncture treatment within 6 months or have participated in other clinical studies. Note: Any patient who meets any of the above criteria will be excluded.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment-Basic;Functional Near Infrared Spectrum;

Secondary

MeasureTime frame
Auditory Verbal Learning Test - Huashan;instrumental activity of daily living,;Hamilton Anxiety Scale;Hamilton Depression Scale;Pittsburgh sleep quality index;

Countries

China

Contacts

Public ContactHe Xia

Sichuan China 81 Rehabilitation Center

1694828730@qq.com15504628546

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026