Mild cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for MCI. (2) Age 50 to 80 years, right-handed, male or female, with a disease duration of more than 3 months. (3) Clinical Dementia Rating Scale (CDR) score of less than 2 (4) Education level elementary school and above, able to understand and complete the scale correctly. (5) Have not received any acupuncture treatment within 6 months (6) Voluntary cooperation and signed informed consent form. Note: Patients who met both of these criteria were included in this study.
Exclusion criteria
Exclusion criteria: (1) Are receiving other treatments that may interfere with cognitive function, such as taking medications that affect cognition (donepezil, memantine, rivastigmine, etc.) (2) Have a history of neurological disorders (except for patients with early suspected Alzheimer's disease) confirmed by examination to affect cognitive function, including encephalitis, epilepsy, Parkinson's disease, vascular dementia, brain tumors, or traumatic brain injury that result in neurological damage and other structural brain abnormalities. (3) Those with a history of tumor, psychiatric disorders (e.g., bipolar disorder, schizophrenia), or severe anxiety (HAMA = 29) and depression (HAMD = 24). (4) The presence of prior alcohol, drug, or substance abuse that can impact on the evaluation of cognitive function (5) Those with bleeding disorders, bleeding tendencies, or severe skin infections (6) Those who have received any acupuncture treatment within 6 months or have participated in other clinical studies. Note: Any patient who meets any of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment-Basic;Functional Near Infrared Spectrum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Auditory Verbal Learning Test - Huashan;instrumental activity of daily living,;Hamilton Anxiety Scale;Hamilton Depression Scale;Pittsburgh sleep quality index; | — |
Countries
China
Contacts
Sichuan China 81 Rehabilitation Center