diabetic retinopathy
Conditions
Interventions
Group A (combined drug group):Diquafosol sodium eye drops and sodium hyaluronate eye drops were used 3 days before surgery, 1 drop/time, 3 times/day, until 1 month after surgery
Group B (monotherapy group):Sodium hyaluronate eye drops were used 3 days before surgery, 1 drop/time, 3 times/day until 1 month after surgery
Sponsors
Xuzhou First People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old; 2. Mild, moderate and severe dry eye; 3. Patients diagnosed with type 2 diabetes mellitus and scheduled for vitrectomy; 4. Preoperative blood glucose was well controlled, and fasting blood glucose was less than 8mmol/L 5. Patients voluntarily participated in the study, signed the informed consent form, and the compliance was good.
Exclusion criteria
Exclusion criteria: 1. Patients with severe dry eye; 2. History of mechanical ocular trauma or corneal refractive surgery or any other surgery affecting the integrity of the ocular surface structure 3. Patients with meibomian gland dysfunction, corneal disease, glaucoma, chronic dacryocystitis, lacrimal canaliculitis, eyelid entropion, eyelid ectropion and other ophthalmic diseases; 4. Patients with autoimmune diseases such as systemic lupus erythematosus, type I diabetes mellitus, Hashimoto's thyroiditis and rheumatoid arthritis; 5. Accompanied by serious primary diseases of the heart, kidney, lung, endocrine, blood or digestive system; 6. Patients with allergy or contraindications to study drugs; 7. Patients with concomitant ocular surface inflammation; 8. Patients with concomitant traction retinal detachment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OSDI questionnaire survey; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal fluorescein staining score;breakup time of tear film; | — |
Countries
China
Contacts
Public ContactSuyan Li
Xuzhou First People's Hospital
Outcome results
None listed