acute ischemic apoplexy
Conditions
Interventions
treatment group:The experimental group was treated with basic treatment regimen + Zhulong Huoxuetongyu granules
control group:The control group received baseline treatment plus placebo
Sponsors
Hospital of Traditional Chinese Medicine affiliated to Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Meeting the diagnostic criteria of ischemic stroke/cerebral infarction in Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018; (2) Qi deficiency and blood stasis syndrome type, according to the TCM syndrome differentiation standards in the Clinical Research Guidelines for the Treatment of Apoplexy with New Chinese Medicines (2010 edition). ? Age of onset: 18 years =80 years; ? Neurological function: NIHSS score =36; ? The patient and/or authorized client give informed consent and sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Patients with intravenous thrombolysis and mechanical thrombectomy were excluded ? Severe disability from previous stroke (mRS=3); ? Severe gastrointestinal diseases (such as intestinal adhesion, intestinal obstruction, intestinal tumor, etc.) in the last 3 months or active gastrointestinal bleeding in the last 1 month or need to fast for some reasons; ? Patients with known severe renal impairment (eGFR < 25mL/min/1.73m 2) were either planning or undergoing dialysis; (5) There are blood system diseases or other conditions leading to abnormal coagulation function; ? Pregnant or lactating women; ? Those who are allergic or intolerant to the drug; ? Participating in other clinical trials; ? patients who were deemed unsuitable for inclusion by the investigator; ? People with malignant tumors or other diseases whose life expectancy is less than six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved Rankin scale;NIHSS score;National Institutes of Health Neurological Deficit Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory cells;Inflammatory cells;Gene sequencing; | — |
Countries
China
Contacts
Public ContactYangSijin
Hospital of Traditional Chinese Medicine affiliated to Southwest Medical University
Outcome results
None listed