Breast Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic code that was diagnosed with invasive breast cancer in the histologic examination (2) Chemotherapy was administered on a standard three-week regimen (3) Female, aged 18-70 (4) Karnofsky score was =75, and the predicted survival time was more than 3 months (5) Without serious cardiovascular and cerebrovascular diseases, digestive diseases, or mental diseases; blood routine examination, liver and kidney function, heart function, and electrocardiogram were normal before chemotherapy (6) Has not received any treatment for breast cancer in the past 1 month (7) Asked for informed consent and voluntary participation
Exclusion criteria
Exclusion criteria: Exclusion Criteria (1)Does not meet the inclusion criteria, the pathological diagnosis was noninvasive breast cancer (2)Using other drugs that affect myelosuppression, such as immunosuppressants and anti-inflammatory drugs (3)Unwilling to participate in or cooperate with treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NEUT;WBC;PLT;HGB; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of neutropenia;Time of G-CSF intervention;stratified analysis;Delayed chemotherapy or not;With or without chemotherapy reduction;Gastrointestinal reactions;Quality of life assessments (QOL);liver and kidney function tests;scale; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhejiang Chinese Medical University