Decreased ovarian reserve
Conditions
Sponsors
Shandong Provincial Third Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: DOR Group: ?AMH<1.1ng/ml ?In the early follicular stage, vaginal ultrasound showed that the number of bilateral ovarian sinus follicles (the number of follicles with a diameter of 2-9mm) AFC < 5-7 ?10IU/L<bFSH<20IU/L The interval between the two tests is greater than 4 weeks, and any of the above two are met, is diagnosed as DOR. (4) 18 years old= age = 40 years old; (5) right-handed; (6) No acupuncture treatment in the past 1 month; Healthy People Group: (1) 18-40 years old; (2) normal ovarian function; (3) Normal immune function and no immune diseases; (4) The patient is informed and signs the informed consent form.
Exclusion criteria
Exclusion criteria: DOR Group: Patients with congenital developmental abnormalities of reproductive organs, bilateral oophorectomy; Endocrine diseases such as polycystic ovary syndrome, hyperprolactinemia, hyperandrogenemia, hypothyroidism, and chronic adrenal insufficiency; Patients with severe cardiovascular and cerebrovascular, liver, kidney, malignant tumors, hematopoietic system and psychiatric diseases; Those with contraindications to magnetic resonance scanning, such as non-removable metal substances installed in the body, claustrophobia syndrome, etc. Healthy People Group: Patients with severe cardiovascular and cerebrovascular,liver,kidney,malignant tumors, hematopoietic system and psychiatric diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kupperman scale;Self-Rating Anxiety Scale;Self-Rating Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| follicle-stimulating hormone;luteinizing hormone;estradiol;Anti-Mullerian bormone;Antral Follicle Counting;rs-fMRI; | — |
Countries
China
Contacts
Public ContactBai Tianyu
Shandong Provincial Third Hospital
Outcome results
None listed