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Common causable pathogen spectrum and trend of severe sepsis/septic shock in children(prospective corhort study)

Study on precision anti-infective therapy for severe sepsis/septic shock in children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070139
Enrollment
Unknown
Registered
2023-04-03
Start date
2022-02-06
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

observation group:NA

Sponsors

Beijing Children's Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
0.1 Years to 18 Years

Inclusion criteria

Inclusion criteria: All patients aged 1 month to 18 years who were admitted to the children's intensive care unit during the study period and were consistent with severe sepsis/septic shock. 1. Severe sepsis was supported by a spanking standard in the 2005 International Expert Consensus on Concepts and Definitions related to Pediatric Sepsis, that is sepsis + any of the following: ? cardiovascular dysfunction, ? acute respiratory distress syndrome (ARDS), ?=2 other organ dysfunction. 2. Septic shock Diagnostic criteria were used in the International Guidelines for Saving Sepsis campaign 2020: Management of Septic Shock and Septic-related Organ Dysfunction in Children, i.e. cardiovascular dysfunction due to severe infection (including hypotension requiring vasoactive medication or abnormal perfusion).

Exclusion criteria

Exclusion criteria: 1. Age: newborns, premature infants with corrected gestational age of less than 41 weeks and adults =18 years old; 2. No pathogen screening were performed 3. clinical data were not completed

Design outcomes

Primary

MeasureTime frame
pathogen;mortality in hospital;

Secondary

MeasureTime frame
ratio of underlying disease;

Countries

China

Contacts

Public ContactQian Suyun
bch_irb@163.com13621381086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026