breast cancer
Conditions
Interventions
One:anesthesia maintained with sevoflurane
Two:anesthesia maintained with sevoflurane and dexmedetomidine
Three:anesthesia maintained with propofol
Four:anesthesia maintained with propofol and dexmedetomidine
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The women undergoing radical surgery for breast cancer under general anesthesia; Age = 18 years old; an American Society of Anesthesiologists Physical Status Classification grade I -?; Informed consent is signed.
Exclusion criteria
Exclusion criteria: Preoperative sleep disturbance (PSQI = 10 points and AIS > 6 points); Preoperative heart rate less than 55 beats/min or atrioventricular block; BMI > 30 kg/m2; Cerebral hemorrhage or stroke; Obstructive sleep apnea hypopnea syndrome; Chronic obstructive pulmonary disease; Severely-impaired liver or kidney function; Long-term use of psychotropic drugs; History of surgery within the last 3 months; Allergies to the drugs or bracelet material involved in this study; Unable to complete the scale involved in this study; Participated in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sleep disturbance at the first three nights after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep structure after surgery (awake, deep sleep, light sleep, rapid eye movement sleep);Anxiety and depression scores;postoperative pain;Postoperative recovery quality;Postoperative adverse events; | — |
Countries
China
Contacts
Public ContactChen Xiuxia
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed