Depression
Conditions
Interventions
Experiment:Huolisu Oral Solution
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 87 Years
Inclusion criteria
Inclusion criteria: 1. The patients after PCI,diagnose coronary heart disease at least one coronary artery has stenosis greater than 70% by coronary angiography 2. 60 years old and above 3. Score >9 on PHQ-9 scale 4. TCM syndrome belongs to "deficiency of liver and kidneyBy coronary angiography"
Exclusion criteria
Exclusion criteria: 1. Take kidney-tonifying Chinese medicine (decoction) or proprietary Chinese medicine at the same time 2. Acute myocardial infarction ?2 years 3. Tumor 4. Target gland diseases (including pituitary, thyroid, adrenal) (excluded according to medical history) 5. Allergic history of Traditional Chinese medicine;A history of drug-induced liver injury;Abnormal liver function, alcoholic liver, fatty liver; 6. Severe complications;In the course of acute onset of chronic disease, or in the course of infectious disease 7. Cognitive dysfunction 8. Previous history of stroke 9. Persons with other mental illnesses;Or is currently using sedatives, antianxiety and other psychotropic medications, and hypnotic and sedative medications =3 times/week 10. Pregnant and lactating women 11. TCM syndrome belongs to external sensation and solid heat syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire-9,PHQ9; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index,ISI;adrenocor ticotropic hormore,ACTH;thyroid stimulating hormone,TSH;T3;T4;FT3;FT4;testosterone,T;Estradiol,E2;Cortisol,COR; | — |
Countries
China
Contacts
Public ContactLu Qing
Outcome results
None listed