sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Over the age of 18; ? It meets the definition of sepsis 3.0; ? The informed consent has been signed.
Exclusion criteria
Exclusion criteria: ? non-sepsis cases; ? Refractory shock (death within 24 hours) or the source of infection cannot be eliminated; ? Advanced tumor; ? Cases that refused active rescue; ? Long-term use of hormone or immunosuppressive therapy, including the application of anti-rejection drugs after organ transplantation; ? Severe craniocerebral trauma (based on craniocerebral CT); 8 points); ? Pregnant or lactating women; ? Patients receiving radiotherapy and chemotherapy within 30 days; ?HIV infection; ? Serious cardiovascular and cerebrovascular events and other factors that require long-term life support.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Charlson comorbidity index;FRAIL Infirmity Scale;IL-6; | — |
Secondary
| Measure | Time frame |
|---|---|
| high-sensitivity C-reactive protein; | — |
Countries
China
Contacts
Tangdu Hospital, PLA Air Force Military Medical University