Autoimmune Thyroiditis
Conditions
Interventions
Treatment Group:Tiaomian Recipe
Control Group:placebo
Sponsors
The Affiliated Hospital to Changchun University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.TPOAb > 300 IU/ml and within the measurable range; 2.FT4 is normal, TSH is normal or elevated, but<10 mIU/L, including subjects taking L-T4; 3.It meets the diagnostic criteria of stagnation of liver-qi and deficiency of spleen and kidney in traditional Chinese medicine; 4.Age from 18 - 70 years old ; 5.Sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Exposure to an iodine-containing radiocontrast dye during the previous 3 months; 2.Currently receiving systemic (oral or injection) glucocorticoid treatment, receiving immunosuppressive agents and immunomodulators, biological agents, and some drugs that may affect the peripheral conversion of T4 to T3 or affect thyroid autoimmunity, such as selenium supplements, vitamin D, amiodarone, propranolol, penicillamine, lithium, and prunella vulgaris preparations; 3.Combined with other autoimmune diseases or malignant tumors; 4.The unstable or acute stage of heart, brain, liver, spleen, kidney, respiratory, blood and other system diseases and complications; 5.Liver function (ALT or AST)>2 times the upper limit of normal value, and/or creatinine (Cr)>the upper limit of normal value; 6.Smoking patients within 6 months; 7.Preparing pregnant, pregnant and lactating women; 8.Patients with mental diseases or dementia; 9.Participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in thyroid peroxidase antibody from baseline to week 24; | — |
Secondary
| Measure | Time frame |
|---|---|
| Thyroid peroxidase antibody at week 12;thyroglobulin antibody;thyroid stimulating hormone;free thyroxine;Quality of Life Questionnaire for Patients with Thyroid Disease;Quantitative scoring of TCM syndromes; | — |
Countries
China
Contacts
Public ContactXiaolin Tong
The Affiliated Hospital to Changchun University of Chinese Medicine
Outcome results
None listed