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Prospective, single-center comparison of 68Ga-DOTATATE and 18F-FDG PET/CT and local PET/MR For EBV positive non-keratonic nasopharyngeal carcinoma Imaging diagnostic value

Prospective, single-center comparison of 68Ga-DOTATATE and 18F-FDG whole-body PET/CT and local PET/MR For EBV positive non-keratonic nasopharyngeal carcinoma Imaging diagnostic value

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300070081
Enrollment
Unknown
Registered
2023-04-01
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal carcinoma

Interventions

Gold Standard:Primary site: biopsy pathology or postoperative pathology Metastasis: confirmed by pathology or follow-up
Index test:The number of lesions and different PET areas of interest between 18F-FDG body PET/CT and local PET/MRI and 68Ga-DOTATATE body PET/CT and local PET/MRI in all included patients were compreh

Sponsors

Department of Nuclear Medicine, West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Non-keratinized nasopharyngeal carcinoma with EBV positive confirmed by pathology and serum, primary or recurrent; 2) Did not receive any treatment within 4 weeks before PET examination; 3) Age =18 years old; 4) Complete clinical data, including age, sex, TNM stage, serum EBV-DNA load, routine imaging, local and systemic treatment history before and after imaging, Ki67 and SSTR2 expression in lesions after biopsy or surgery.

Exclusion criteria

Exclusion criteria: 1) Pregnant or lactating women; 2) Complicated with other malignant tumors; 3) Can not sign the scanned informed consent.

Design outcomes

Primary

MeasureTime frame
maximum standard uptake volume, SUVmax;metabolic tumor volume, MTV;total lesion glycolysis, TLG;SSTR expressing tumor volume, SRETV;total lesion SSTR expression, TLSRE;—

Countries

China

Contacts

Public ContactRui Huang

Department of Nuclear Medicine, West China Hospital, Sichuan University

huang_rui@scu.edu.cn18980605781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026