Effificacy of Sodium Tanshinone IIA Sulfonate combined with hydration pretreatment for prevention of contrast-induced acute kidney injury in patients after percutaneous coronary intervention

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300070064

Enrollment

Unknown

Registered

2023-03-31

Start date

2023-04-01

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

contrast-induced acute kidney injury

Interventions

Sodium Tanshinone IIA Sulfonate Group:STS?80mg,was diluted in 250 mL of 0.9% saline and administered intravenously over 2 hours period before and 3 days after the operation)

Control Group:only received hydration

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.at least 18 years of age 2.scheduled for an elective cardiac intervention

Exclusion criteria

Exclusion criteria: 1. contraindications to the contrast 2.acute myocardial infarction requng primary coronary intervention 3. heart failure with LVEF < 30% or cardiogenic shock 4.acute renal failureiri 5. hepatic failure 6.concomitant use of nicorandil or trimetazidine 7.hemodialysis.

Design outcomes

Primary

Measure	Time frame
serum creatinine;cystatin C;	—

Secondary

Measure	Time frame
blood urea nitrogen;C-reactive protein;	—

Countries

China

Contacts

Public ContactTeng Wei

The First Affiliated Hospital of Henan University

tw221618@126.com+86 371 22736829

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026