Influenza A
Conditions
Interventions
Integrative Medicine Group(retrospective):NA
Western Medicine Group(retrospective):NA
Integrative Medicine Group(prospective):NA
Healthy Control Group(prospective):NA
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
14 Years to 83 Years
Inclusion criteria
Inclusion criteria: 1.Retrospective study (1) Patients aged = 14 years. (2) Have the clinical manifestations of influenza. (3) Influenza A virus antigen test positive. (4) Treatment with oseltamivir and/or Xu's influenza decoction. 2. Prospective study (1) The course of disease = 48 h and body temperature = 38 °C. (2) At least one respiratory symptom ( nasal congestion, sore throat, cough ), and at least one systemic symptom (fever, headache, muscle pain, aversion to cold or sweating, fatigue ). (3) Influenza A virus antigen test positive. (4) Age = 18 years and = 65 years. (5) Patients informed and agreed to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Retrospective study (1) In line with the ' critical case ' criteria, such as respiratory failure. (2) Patients with end-stage renal disease, malignant tumor and other serious basic diseases or mental diseases. (3) Patients with body temperature less than 37.3 °C on admission. (4) Patients who received influenza decoction treatment and increased traditional Chinese medicine > 5 flavors on its basis. (5) Course of disease less than 2 days. 2.Prospective study (1) In line with the ' critical case ' criteria, such as respiratory failure. (2) Pregnant or puerperal women. (3) Patients with end-stage renal disease, malignant tumor and other serious basic diseases or mental diseases. (4) Receive influenza vaccination within 12 months. (5) Allergic constitution or drug allergy (history). (6) has taken antiviral drugs or other Chinese medicine treatment of influenza.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to defervescence(retrospective);Cumulative antipyretic rate(retrospective);Immune cells and cytokines(perspective);curative effect of TCM syndromes(effective rate, perspective); | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine and CRP(retrospective);Length of stay(retrospective);Medical costs(retrospective);Subgroup analysis on time to defervescence(retrospective);Symptom relief time(perspective);Secondary complications ( prospective );Blood routine and CRP (prospective );Length of stay(prospective);Medical costs(prospective); | — |
Countries
China
Contacts
Public ContactShuyan Fu
The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed