Ureteral calculus
Conditions
Interventions
group P:Total intravenous infusion of propofol
group R:Total intravenous pumping of rimazole
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary participation and the ability to provide informed consent; 2. ASA classification I~III; 3. Patients undergoing selective ureteroscopic holmium laser lithotripsy; 4. Aged 18-75 years, BMI 18-30 kg/m2; 5. Not participated in clinical trials of other drugs in the three months before screening.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to the active ingredients or all excipients of remazolam and benzodiazepines; 2. Patients with schizophrenia and severe depression; 3. Patients taking sedative and hypnotic drugs for a long time; 4. Complicated with other important organ dysfunction: including severe liver and kidney dysfunction; Cerebral organic diseases, specifically aneurysmal vascular diseases or arteriovenous malformations and cerebral hemorrhage; Severe hypertension, coronary heart disease, cardiac insufficiency (NYHA >= grade III), pulmonary hypertension; Hematological diseases; Abnormal coagulation function; Severe respiratory diseases; 5. Patients considered unsuitable for inclusion by other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Procalcitonin (PCT); | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure (BP);heart rate (HR);C-reactive protein (CRP); | — |
Countries
China
Contacts
Public ContactXiaoxia Gu
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed