Recovery quality of general anesthesia
Conditions
Interventions
Remazolam group:Remazolam toluenesulfonate 0.3~1.0 mg/kg/h maintenance anesthesia
Propofol group :Propofol 4-6 mg/kg/h for maintenance anesthesia
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. All patients had indications for laparoscopic surgery and anesthesia; 2. American Association of anesthesiologists (ASA) grade: Grade I-II; 3. It can complete the observation of various indexes before and after operation; 4. Aged 30-60 years; 5. Patients' informed consent to the study.
Exclusion criteria
Exclusion criteria: 1. Patients with serious cardiovascular and cerebrovascular diseases; 2. Unable to tolerate laparoscopic surgery or serious postoperative complications; 3. Allergic to narcotic drugs used in this study; 4. Patients with long-term use of narcotic analgesics, sedatives or non steroidal anti-inflammatory drugs; 5. Opioid dependent or opioid tolerant; 6. Patients with systemic hypotension despite the use of vasoactive drugs; 7. Bradycardia, heart rate < 55 beats/min; 8. High atrioventricular block without pacemaker; 9. Complicated with craniocerebral injury and intracranial hypertension; 10. Patients with severe cardiac, pulmonary, liver and renal dysfunction; 11. Previous allergic disease history; 12. Previous mental disease history; 13. Fat metabolism disorder; 14. Predictably difficult intubation; 15. The investigator judged that the subject was not suitable to participate in the clinical trial and was unable to cooperate to complete the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Awakening quality score;Extubation time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory recovery time;Adverse reactions after surgery; | — |
Countries
China
Contacts
Public ContactGu Xiaoxia
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed