Tropisetron in prevention of rebound pain and anxiety after upper extremity surgery under brachial plexus anesthesia: A randomized, double-blind, parallel controlled clinical study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300069994

Enrollment

Unknown

Registered

2023-03-30

Start date

2023-04-01

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with brachial plexus anesthesia

Interventions

control:nomal saline 5ml iv

Tropisetron:Tropisetron 5mg iv injection

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-70 years, ASA grade I-III, undergoing upper extremity surgery under brachial plexus anesthesia, were enrolled in the clinical trial voluntarily.

Exclusion criteria

Exclusion criteria: Shock or coma; history of psychiatric illness and long-term use of psychotropic drugs; cognitive impairment; pregnant or lactating women; History of drug dependence; use of other sedative and analgesic drugs in the past week; Participated in clinical trials of Tropisetron as a subject within the last 3 months; anyone allergic to tropisetron, any contraindications to lidocaine, ropivacaine, midazolam, Sufentanil, cis-atracurium, tropisetron, propofol, diclofenac, patients on 5HT3 blockers.

Design outcomes

Primary

Measure	Time frame
postoeprative pain;Anxiety scores;	—

Countries

China

Contacts

Public ContactXingrui Gong

Xiangyang Central Hospital

gongxrhbxy@sohu.com+86 15071551981

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026