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Influence of Anesthesia Mode Selection on Postoperative Pancreatic Leakage in Patients with pancreatic cancer after Neoadjuvant Chemotherapy

Influence of Anesthesia Mode Selection on Postoperative Pancreatic Leakage in Patients with pancreatic cancer after Neoadjuvant Chemotherapy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069978
Enrollment
Unknown
Registered
2023-03-30
Start date
2023-03-31
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic cancer

Interventions

control group:General anesthesia+epidural block+epidural analgesia
Test group:General anesthesia+transverse abdominal fascia plane block+intravenous analgesia

Sponsors

Department of Anesthesiology, Shanghai Changhai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Age >= 18 2) Selective radical surgery for pancreatic cancer; 3) The clinical data required for the study are complete (including general factors, test indicators, anesthesia factors, surgical factors, etc.); 4) According to the international standard of mature high-throughput pancreatic surgery center, there are 40 pancreatic operations per year. Only patients with an annual surgical volume of more than 40 and who have independently guided and performed such operations for more than 3 years can be included.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of chronic pain and preoperative use of analgesics 2) Receive hormone or steroid treatment before operation 3) Previous neuromuscular disease 4) Past cognitive impairment 5) There are contraindications of paravertebral block and intraspinal puncture (severe coagulation dysfunction, infection or local anesthetic allergy history) 6)18.5kg/m2 >= BMI >=30kg/m2 7) Organic heart disease or serious arrhythmia 8) Emergency surgery 9) Patients undergoing upper abdominal surgery again 10) Refuse to participate

Design outcomes

Primary

MeasureTime frame
POPF;

Secondary

MeasureTime frame
Other abdominal complications;Postoperative AKI;Cardiovascular and cerebrovascular events;Postoperative pulmonary complications;

Countries

China

Contacts

Public ContactXu Tao

Shanghai Changhai Hospital

413650671@qq.com+86 135 0197 6460

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026