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Application of Remazolam combined with lidocaine-prilocaine cream in perioperative invasive pain puncture

Application of Remazolam combined with lidocaine-prilocaine cream in perioperative invasive pain puncture

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069970
Enrollment
Unknown
Registered
2023-03-30
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal anesthesia and nerve block

Interventions

Advanced care 1:Apply lidocaine ointment to the puncture operation site, and give the same volume of physiological saline intravenously
Advanced care 2:Apply lidocaine ointment to the puncture operation site and intravenous administration of remidazolam toluenesulfonate
control:Apply skin cream to the puncture site, and give the same volume of physiological saline intravenously

Sponsors

The first affiliated hospital of Jinan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (i) patients had a full understanding of the purpose and significance of this trial and were able to sign an informed consent form; (ii) patients were 18–60 years old and had American Society of Anesthesiologists Physical Status (ASA PS) I to II with BMI of 18-30 kg/m2; (iii) patients underwent nerve-blocking anesthesia and intraspinal anesthesia.

Exclusion criteria

Exclusion criteria: (i) patients allergic to sedative drugs and lidocaine-propitocain cream; (ii) patients had contraindications of nerve block-ing anesthesia and intraspinal anesthesia; (iii) patients had sleep apnea syndrome, severe snoring, obesity, acute upper respiratory infections, asthma, and smoking that may lead to serious respiratory events during the perioperative period; (iv) patients with pre-existing neurological disease or clinically obvious neurovascular disease or patients with unconsciousness. (v) patients with severe respiratory or circulatory disease ; (vi) patients who were blind, deaf, and non-native Chinese language so unable to complete the NRS grade; (vii) patients underwent cesarean section; (viii) other circumstances in which the investigator determined that a patient was not suitable for participation in the clinical trial.

Design outcomes

Primary

MeasureTime frame
NRS;anxiaty score;

Secondary

MeasureTime frame
patient's satisfaction;hemodynamics;adverse events;

Countries

China

Contacts

Public ContactHu Donghua

The first affiliated hospital of Jinan University

15360842720@163.com+86 189 2750 1281

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026