Anesthesiology
Conditions
Interventions
Group C:No remote ischemic preconditioning
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: ASA Grade I to III, age =60 years, BMI18-25 kg/m2.
Exclusion criteria
Exclusion criteria: Those complicated with hypertension, heart disease or other basic diseases before operation; Patients with central nervous system or mental illness before surgery, or diagnosed with cognitive dysfunction; Long-term use of antipsychotics, sedatives and hormones before surgery; People with long-term alcoholism, drug addiction or drug dependence; Dysfunction of vital organs; The internal environment is seriously disturbed; Other diseases that interfere with the assessment of cognitive function; Unable to communicate; illiterate. Preoperative simple Mental Scale (MMSE) score <=24 points; Monitor site trauma or surgery can not be monitored.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SjvO2;Da-jvO2;CO2ER;MoCA;MMSE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient basic information;Hemodynamics;anesthesia induction time;operation time;wake up time;CRP;NSE;IL-1b;TNF-a;S100B;Abnormal sensation or movement of the right upper arm;Postoperative bleeding or fever; | — |
Countries
China
Contacts
Public ContactLiu Weiwei
Weifang People's Hospital
Outcome results
None listed