osteoarthritis of the hip, osteonecrosis of the femoral head (Ficat IIIB or IV), and developmental dysplasia of the hip.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients who need unilateral primary THA surgery due to osteoarthritis of the hip joint, joint destruction, aseptic necrosis of the femoral head, femoral neck fracture, etc; (2) The age is 18-80 years old, regardless of gender; (3) Body mass index: 20-35 kg/m2; (4) The preoperative American Society of Anesthesiologists (ASA) anesthesia risk assessment was graded as Grade I-III; (5) Patients who have signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Long-term use of opioids (daily or almost daily use of opioids>3 months); (2) Alcohol or drug abuse or allergy to any drugs (local anesthetics, etc.) used in this study; (3) Psychopaths, language disorders, and inability to complete the visual analog scale (VAS); (4) Patients with neuropathy of the extremities on the surgical side have moderate or more joint deformities or stiffness on the surgical side; (5) Previous history of hip trauma, or bilateral hip sensory asymmetry; (6) Local skin infection and bleeding at the anesthesia puncture site; (7) Abnormal coagulation function (PT, APTT exceeding normal values, INR<=1.4), platelet count<80 × 109/L), patients with possible abnormal platelet function; (8) The surgeon or anesthesiologist believes that the patient is not suitable for inclusion; (9) Patients with surgery time greater than 90 minutes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dosage of morphine within 24 h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total morphine consumption during hospitalization;Intraoperative consumption of opioids;Postoperative Visual Analogue Scale Score at rest;Postoperative Visual Analogue Scale Score at motion;Postoperative quadriceps strength;Time until the first walkout of bed after surgery;postoperative adverse events;Time to hospital discharge; | — |
Countries
China
Contacts
West China Hospital, Sichuan University