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Effect of hand-foot fuming-washing with Qufeng Huoxue Prescription on prevention and treatment of paclitaxel induced peripheral neuropathy

Effect of hand-foot fuming-washing with Qufeng Huoxue Prescription on prevention and treatment of paclitaxel induced peripheral neuropathy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069949
Enrollment
Unknown
Registered
2023-03-30
Start date
2021-05-17
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

advanced lung cancer

Interventions

trial group:Qufeng Huoxue Prescription
control group1:oral vit B1
control group2:warm water soaking

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Patients with advanced lung cancer were diagnosed by imaging and pathology; (2) The life expectancy of patients with advanced lung cancer is more than 6 months; (3) The PS (physical function state) score of patients with advanced lung cancer is 0-2 points; (4) They received chemotherapy containing taxanes for 4-6 cycles and maintenance treatment, with a weekly period of 3 weeks (21 days); (5) The condition is stable in the past 2 weeks (before participating in the study); (6) No restriction on sex, smoking or not; (7) Obtain written informed consent.

Exclusion criteria

Exclusion criteria: (1) The skin of the patient's hands and foot is broken and cannot be fumigated; (2) Patient is participating in another clinical trial; (3) Incapacity and researcher believes that patient is not suitable for the study.

Design outcomes

Primary

MeasureTime frame
NCI-CTCAE 2-3 grade;

Secondary

MeasureTime frame
FACT/GOG-Ntx;Neuropathic pain scale, NPS;change chemotherapy dosage due to PIPN;

Countries

China

Contacts

Public ContactYuanlin Song

Zhongshan Hospital, Fudan University

song.yuanlin@zs-hospital.sh.cn+86 150 2175 7762

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026