postpartum depression
Conditions
Interventions
Esketamine group:Cut the peritoneal immediate intravenous escitalopram ketamine 0.15 mg/kg (diluted saline to 5 ml)
Control group:Cut the peritoneal immediate intravenous equal volume normal saline
Sponsors
Wenzhou People's Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 40 Years
Inclusion criteria
Inclusion criteria: 60 cases of elective singleton primiparous women undergoing cesarean section, inclusion criteria: 1) The results of preoperative fetal umbilical blood flow and fetal monitoring (NST) were normal; 2) The gestational age was 37-41 weeks; 3) ASA I-II 4) Age 21-40 years old;
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications to spinal anesthesia (including coagulation disorders, spinal trauma or deformity, etc.); 2) Patients with elevated blood pressure, intraocular pressure and intracranial pressure; 3) Those who are allergic to ketamine components;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neonatal umbilical cord blood of blood gas analysis and Apgar score;Prenatal and postpartum 42 days of Edinburgh depression scale (EPDS) questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| I-DI;T-DI;U-DI;Vital Signs;VAS;OAA/S;Adverse reaction; | — |
Countries
China
Contacts
Public ContactZheng yanya
Outcome results
None listed