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A split-face evaluation of the efficacy and safety of bipolar radiofrequency microneedling compared with mono-polar mode

A split-face evaluation of the efficacy and safety of bipolar radiofrequency microneedling compared with mono-polar mode

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069921
Enrollment
Unknown
Registered
2023-03-29
Start date
2023-03-23
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

photoaging

Interventions

Bipolar mode:Bipolar mode of radiofrequency microneedling therapy
Monopolar mode:Monopolar mode of radiofrequency microneedling therapy

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Individuals with skin aging, characterized by changes in skin texture such as decreased skin elasticity, surface relaxation or sagging, appearance of fine lines, facial spots, pigmentation, epidermal hyperplasia, vascular atrophy or proliferation. (2)Participants who are informed of and have signed the informed consent form for this study. (3)Age range: 18-65 years old.

Exclusion criteria

Exclusion criteria: (1) Individuals who are known to be intolerant to radiofrequency microneedling treatment. (2) Patients with active or progressive skin diseases in the treatment area, or skin diseases with isomorphic reactions, such as eczema, psoriasis vulgaris, and lichen planus. (3) Facial viral, bacterial, or fungal infections. (4) Severe comorbidities such as cardiovascular disease, poorly controlled diabetes, or malignancy. (5) Patients with keloid scars or a predisposition to scarring. (6) Individuals with psychiatric disorders who cannot cooperate. (7) Pregnant or breastfeeding women or those planning to become pregnant. (8) Patients who have received other facial cosmetic treatments within the last month (including facial plastic surgery).

Design outcomes

Primary

MeasureTime frame
Clinical grading of photoaging;Clinical grading of Hyperpigmentation;Appearance of wrinkles;

Secondary

MeasureTime frame
Clinical grading of elasticity;Stratum Corneum Hydration;Transepidermal Water Loss;Safety profile assessment;Visual Analogue Scale;

Countries

China

Contacts

Public ContactXiang Wen

West China Hospital, Sichuan University

xiangwen_wcums@163.com+86 153 5120 0113

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026