Skip to content

Efficacy and safety of edaravone dextromethorphan combined with aspirin and clopidogrel in the treatment of acute non-cardiogenic mild ischemic stroke in the real world

Efficacy and safety of edaravone dextromethorphan combined with aspirin and clopidogrel in the treatment of acute non-cardiogenic mild ischemic stroke in the real world

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069917
Enrollment
Unknown
Registered
2023-03-29
Start date
2023-03-30
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular disease

Interventions

Exposure group: Edaravondexcamphorol was used, and the compatibility and timing of administration were not specified according to clinical practice.:N/A
Non-exposed group: Edaravondexcamphenol was not used, and compatibility was not defined according to clinical practice:N/A

Sponsors

Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 89 Years

Inclusion criteria

Inclusion criteria: 1) Age 18-89 years old. 2) Acute non-disabling ischemic stroke (randomized NIHISS= 4 score) was classified as non-cardiogenic ischemic stroke according to the TOAST score. Informed consent was obtained and participants agreed to participate. 3) The time from the onset of stroke to hospital admission is no more than 7 days.

Exclusion criteria

Exclusion criteria: 1) Pregnant or lactating patients and planned pregnancy within 90 days. 2) Patients with severe renal failure (eGFR < 30ml/min). 3) Patients with serious mental disorders or dementia who cannot cooperate to complete informed consent and follow-up. 4) Patients complicated with malignant tumors or severe systemic diseases with an estimated survival time of less than 90 days.Have participated in, or are currently enrolled in, another clinical intervention study within 30 days of enrollment.

Design outcomes

Primary

MeasureTime frame
mRS Score;90 days of new stroke events;

Secondary

MeasureTime frame
NIHSS scale score;safety;

Countries

China

Contacts

Public ContactWu Yuan

Guangxi Medical University

wuyuan90@126.com+86 136 0771 3316

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026